产品详情
EGFR(E746-A750)del [26235]
[100ul]
Catalog Number: 26235 |
Gene Symbol: EGFR/HER1/ERBB1 |
Description: Anti EGFR(E746-A750)del Mouse Monoclonal Antibody |
Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK ERK, PI3 kinase AKT, PLCgamma PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR). |
Immunogen: A synthetic peptide from the internal region of EGFR which includes the deletion of E746-A750, human origin. |
Applications: ELISA, WB |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 |
Concentration: 1 mg/ml |
Host: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: |
Purity: Purified from ascites |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes EGFR(E746-A750), but not wild type EGFR of vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Download Datasheet: |
Western blot: |
Western blot analysis of recombinant EGFR(E746-A750) and wildtype proteins. Purified His-tagged EGFR(E746-A750)del protein (aa 702-987) and wild-type protein (aa 702-987) were blotted with anti EGFR(E746-A750)del mouse antibody (Cat. #26235). |
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